[The influence of acizolum to bioelements content in rat's blood plasma, parenchimal organs and brain]. / Vliianie atsizola na soderzhanie bioélementov v plazme krovi, parenkhimatoznykh organakh i golovnom mozge krys.

Zinc content in blood plasma and brain tissue of rats was studied by analytic mass-spectrometry with inductively coupled plasma. In control (saline-treated animal) zinc content in plasma was 3.6±1.4 mg/ml, in the liver - 12.5±2.5 mg/mg, in the spleen - 10.9±4.1 mg/mg, in the brain - 8.7±3.0 mg/mg. After a single intraperitoneal injection of zinc donator acizolum (24 mg/kg) zinc content decreased in all examined tissues, especially in brain. After a course of sequential acizolum injections (seven administrations during two weeks) essential elevation of zinc content in blood plasma and tissues investigated was detected. The maximal increase zinc concentration in blood plasma and liver was detected in 15 h after the last acizolum injections. Selen, calcium, copper and iron contents demonstrated a more complex behaviour. The obtained data suggest that prolonged acizolum administration has a significant impact on the bioelements content, and this should be taken into consideration when this zinc donator is used as a drug.

Effects of Acyzol on Zinc Content in Rat Brain and Blood Plasma.

Zinc level in the blood plasma and brain of rats was studied by inductively coupled plasma mass spectrometry. Maximum amount of zinc was observed in the cerebellum (15.0±5.5 µg/mg wet tissue). Single intraperitoneal administration of a zinc donor acyzol (24 mg/kg) did not change the content of this element in the tissues. Repeated injections of acyzol (7 injections over 14 days) significantly increased zinc level in rat plasma and brain. This elevation was most pronounced in the forebrain (cortex and subcortical structures). The rise in zinc concentration in blood plasma correlated with its level in the brain.

[The health indices of those working in the cleanup during accident recovery operations]. / Nekotorye pokazateli zdorov'ia likvidatorov v period avariino-vosstanovitel'nykh rabot.

Having analyzed the data base of All-Army register contained information about 35,970 rescuers it was determined that 45.5% of them during works in dangerous radiative conditions complained of the health change for the worse characterized by the state of irritation of mucous membrane of superior respiratory and gastrointestinal tracts. The direct correlation between value of irradiation dose and frequency of complaints, and also degree of lowering of there physical performance have been defined.

[A hygienic analysis of the irradiation doses of those cleaning up the aftermath of the accident at the Chernobyl Atomic Electric Power Station (based on data from the All-Army Registry)]. / Gigienicheskii analiz doz oblucheniia uchatnikov likvidatsii posledstvii avarii na Chernobyl'skoi AES (po dannym Vsearmeiskogo registra).

In the result of the analysis of irradiation doses of 36,895 servicemen who have participated in liquidation of the Chernobyl APC disaster consequences it was found out that the average radiation dose was 12.1 cSv in 1986, 8.4 cSv in 1987, and in 1988-90 it didn't exceed 5 cSv. The irradiation received by these servicemen has depended on the time of their arrival to the zone of the disaster, the maximum permissible doses of radiation established at that period, the character of their activities and the place of their work, utilization of protection means. A conclusion was made that irradiation dose itself could be considered only as a general guide reference, because it didn't take into consideration internal irradiation and beta-irradiation of skin. That's why it is necessary to continue the further monitoring over the health status of liquidators independently of the doses of irradiation which were fixed in their histories.

[The importance of the All-Army Registry in the health assessment of the servicemen who took part in the cleanup of the aftereffects of the accident at the Chernobyl Atomic Electric Power Station]. / Znachenie Vsearmeiskogo registra v otsenke zdorov'ia voennosluzhashchikh, prinimavshikh uchastie v likvidatsii posledstvii avarii na ChAES.

An active part in liquidation of the Chernobyl APS disaster consequences was taken by servicemen. The article deals with the so-called All-Army Register and its tasks which are as following: a long-term records of patients who have participated in this emergency situation and received various doses of radiation; control over the changes in their health status, etc.